Time and place: T 2:00-4:10; UH 438
Instructors: Barbara Finlay, Shimon Edelman.
In this course, we will integrate computational modeling with known neurophysiology as it applies to large nervous systems. In some cases, the relationship of present modeling is direct (Themes I-III); or the biology needs more computational instruction (IV); or the computation is interesting but the application obscure (V). We will spend 2-3 weeks on each subject, with half of the first sessions of each devoted to a basic overview of the relevant computational principles and neuroanatomy/physiology in each case. We encourage you to take this course if you have prior experience in either computation or neurobiology: the point of the course is making the links.
| theme # | heading | example systems |
| THEME I | FEEDFORWARD COMPUTATION: Bayesian inference and decision making |
Multisensory integration; visuomotor decision-making |
|---|---|---|
| THEME II | SEQUENCE REPRESENTATION AND PROCESSING | Birdsong; applications to language |
| THEME III | INFORMATION INTEGRATION AND CONTROL: Parallel computations |
Complementary roles of cortex, basal ganglia, hippocampus and cerebellum |
| THEME IV | HIGHLY DISTRIBUTED SYSTEMS | Integration of innate and learned patterns in amygdala; gating in attachment systems; semantic knowledge |
| THEME V | OPEN-ENDED COMPUTATION | to be determined |
icon to see the class notes for each week
(future material always under construction).
| week/date | theme | topic | remarks/extras |
|---|---|---|---|
| week 1: 1/22 ![]() |
Theme I: feedforward computation |
Introduction and overview. The role of computation in cognition. Statistical inference. The Bayesian framework. |
Click on the icon on the left to see the class notes for
this week.
|
| week 2: 1/29
|
Theme I: feedforward computation |
Bayesian neural coding. Multisensory integration. |
Click on the icon on the left to see the class notes for
this week. Shimon will discuss the papers by Deneve (2007) and by Knill &
Pouget (2004). As always, the papers themselves are under readings.
|
| week 3: 2/5
|
Theme I: feedforward computation |
Bayesian decision-making and motor control. | There is an extra reading (optional) for next Tuesday: *Using Bayes' Rule to Model Multisensory Enhancement in the Superior Colliculus, T. J. Anastasio, P. E. Patton, and K. Belkacem-Boussaid, Neural Computation 12:1165-1187 (2000). |
| week 4: 2/12 ![]() |
Theme II: sequences |
Neural synchrony, or not | Singer; Shadlen |
| week 5: 2/19
|
Theme II: sequences |
Synfire; polychronization; spike-timing dependent plasticity (STDP) |
Ikegaya; Izhikevich; Jun and Jin |
| week 6: 2/26
|
Theme II: sequences |
Birdsong
Language |
Farries & Perkel; Yu & Margoliash; Drew & Abbott;
Dominey Optional extra: *What songbirds teach us about learning, M. S. Brainard and A. J. Doupe, Nature 417:351-358 (2002). |
| week 7: 3/4
|
Theme III: information integration |
Roles of hippocampus, cortex, basal ganglia, cerebellum |
Atallah et al.; Doya
[Remember the take-home question: use the O'Reilly/ Doya basal ganglia model to produce some serially ordered behavior, one of your favorite serially ordered behaviors.] |
| week 8: 3/11 ![]() |
Theme III: information integration |
Inverse models; models of high-level cognition | An extra paper, Internal models for motor control and trajectory planning, M. Kawato, Current Opinion in Neurobiology 9:718-727 (1999); also O'Reilly, and the extra extra papers listed on the notes page for this week. |
| Spring Break | |||
| week 9: 3/25 ![]() |
Theme III: information integration |
Lifetime memory integration | Merker |
| week 10: 4/1 ![]() |
Theme IV: highly distributed computation |
The amygdala | Martinez-Garcia et al.; A. Pitkanen; also an extra: *Emotion Circuits in the Brain, J. E. LeDoux, Annual Review of Neuroscience, 23:155-184 (2000). |
| week 11: 4/8 ![]() |
Theme IV: highly distributed computation |
The amygdala (cont.) | Young, Goodson, and Zald. |
| week 12: 4/15 ![]() |
Theme IV: highly distributed computation |
|
|
| week 13: 4/22 ![]() |
Theme V: open-ended computation |
novel models of computation |
Maass [maybe also Fernando, C. and Sojakka, S. (2003). Pattern recognition
in a bucket. In Banzhaf, W., Christaller, T., Dittrich, P., Kim, J.T. and
Ziegler, J., editors, Advances in Artificial Life, Proceedings of the 7th
European Conference on Artificial Life (ECAL 2003), pages
588-597. Springer. See Fernando's publication page]
Barrett |
| week 14: 4/29 ![]() |
Theme V: open-ended computation |
evolution and emergence |
Gould, S. J. (1986), Evolution and the Triumph of
Homology, or Why History Matters, American Scientist 74:60-69.
Finlay, B. L. (2007) Endless minds most beautiful, Developmental Science 10:30-34. Szathmary & Maynard Smith Clayton & Kauffman |
Shimon Edelman <s e 3 7 at c o r n e l l . e d u> Last modified on Sun Apr 27 12:08:09 2008